Lichen planus may affect the skin cutaneous lichen planus, oral cavity oral lichen planus, genitalia penile or vulvar lichen planus, scalp lichen planopilaris, nails, or esophagus. These mechanisms may combine to cause t cell accumulation in the. It is a form of acquired dermal macular hyperpigmentation. Rare lichen planus genetic and rare diseases information. Lichen planus is an uncommon disorder of unknown cause that most commonly affects middleaged adults. The use of topical corticosteroides in the treatment of oral lichen.
Lichen planus lesions are described using the six ps planar. Lichen planus pigmentosus lpp was first described by bhutani et al. Differential metallothionein expression in oral lichen planus and. Pada kulit, lichen planus ditandai dengan adanya ruam kecil merah keunguan yang kadang terasa gatal.
Skin lichen planus, scleroderma, maculopapular rash, hyperkeratosis. The lesions of cutaneous lichen planus typically resolve within12 years, whereas the lesions of oral lichen planus are long lasting and persist for 20 years resolution of the white striations, plaques, or papules is rare. In the mouth, lichen planus may t ake on two basic forms. If caused by medication or fillings, lichen planus will clear after the treatment is stopped or the fillings removed.
Most people can manage typical, mild cases of lichen planus at home, without prescribed medical treatment. A pigmented variant of lichen planus lp was first reported from india in 1974 by bhutani et al. It leads to the severe destruction of the epithelial basal layer. Evidence suggests it may be an autoimmune disorder. Oral lichen planus olp is a chronic inflammatory, immune mediated disease that affects the oral mucosa and skin. Plaquetype variant of reticular oral lichen planus with erosive areas involving the dorsum of the tongue. Lichen planus is an intensely itchy pruritic inflammatory lesion of the skin. On the skin, lichen planus appears as small, itchy, redpurple, flattopped bumps that occur in clusters on the forearms and thighs primarily.
It may be found with other diseases of altered immunity, such as ulcerative colitis, lichen sclerosis, myasthenia gravis etc. You cant catch lichen planus or give it to another person. Lp most commonly presents as itchy, shiny, reddishpurple spots lesions on the skin cutaneous lp or as whitegray lesions in the mouth or on the lips oral lp. Powerpoint presentation ppt of lichen planus an informative powerpoint presentation on the causes and effects of lichen planus. Lichen planus of the glans penis jama dermatology jama.
Usatine, md, and michelle tinitigan, md, university of texas health science center, san antonio, texas l ichen planus is a chronic, inflam. Lichen planus is a recurrent, pruritic, inflammatory eruption characterized by small, discrete, polygonal, flattopped, violaceous papules that may coalesce into rough scaly plaques, often accompanied by oral andor genital lesions. Pdf tantangan dalam perawatan oral lichen planus pada. Common symptoms reported by people with lichen planus.
In many of its features it is so like an infectious disease, and especially so like syphilis, that some observers surmise that it may be owing to a generalized microorganism. It is characterized by polygonal, flattopped, violaceous papules and plaques with overlying, reticulated, fine white scale wickhams striae, commonly affecting dorsal hands, flexural wrists and forearms, trunk, anterior lower legs and oral mucosa. Lichen planus is a condition that forms a very itchy rash on the skin or in the mouth. It is usually temporary, lasting 10 years, on average, and most often affects adults between the ages of 30 and 60. Sometimes lichen planus affects areas of skin where you had a cut or burn. Oral lichen planus olp is a common disorder that affects stratified. Lichen planus is thought to be an autoimmune process that causes. These mechanisms may combine to cause tcell accumulation in the superficial lami na propria.
Though conventional therapies have aimed to alleviate the signs and. Lichen planus and oral cancer oral, head, and neck. So when i was given metformin i was trying to be careful, but within two months i developed lichen planus, which is the same thing that my mother had. Lichen planus is a cellmediated immune response of unknown origin. Oral lichen planus, topical corticosteroids, triamcinolone acetonide, questionnaire. The disease principally affects the sunexposed areas of the body such as the face, trunk, and upper. Lichen planus gejala, penyebab dan mengobati alodokter.
Aug 17, 20 oral lichen planus is a chronic inflammatory disease. Lichen planus is a recurrent chronic inflammatory disorder that affects the skin, mucous membranes, genitalia, scalp lichen planopilaris and nails characterized by itchy patches, lesions or rashes. Mild cases can be treated with fluorinated topical steroids. Exposure to certain medicines, dyes, and other chemicals including gold, antibiotics, arsenic, iodides, chloroquine, quinacrine, quinide, phenothiazines, and. Lichen planus lp is a rare, chronic, inflammatory autoimmune skin and mucous membrane disease. Nonspecific mechanisms include mast cell degranulation and matrix metalloproteinase mmp activation in olp lesions. Oral lichen planus is a chronic inflammatory, a noninfectious disease that causes lesions on the buccal mucosa, tongue andor gums. Lichen planopilaris usually affects young adult women, although the age range is wide and it also affects men. Lichen planus adalah peradangan yang terjadi pada kulit, rambut, kuku, dan selaput lendir mukosa. Classic lichen planus often goes away after a few months or years, although it may return. Pdf purpose oral lichen planus olp is a chronic oral mucosal disease that has been recognized as an immune condition. If this is the case, treatment may not be necessary. A 19yearold girl found excellent results in relief in lichen planus pigmentosa with homeopathy at life force a 19yearold girl, miss.
Oral lichen planus olp is a chronic inflammatory condition that effects oral mucous membranes with a variety of clinical presentations including reticular, atrophic, plaque and ulcerative lesions. Oral lichen planus olp is a tcellmediated chronic inflammatory oral. It commonly develops in association with lichen planus affecting the skin, mucosa and nails. Lichen planus is now regarded as a constitutional disease with local manifestations on the skin and mucous membranes. Lichen planus nord national organization for rare disorders. When lichen planus develops in the mouth, it often does not cause pain or other symptoms.
More severe cases, especially those with scalp, nail, and mucous membrane involvement, may need more intensive therapy. It affects approximately 12% of the general adult population. Lichen planus lykin planus is a chronic condition that affects the skin and the lining of the mouth. The pathogenesis of oral lichen planus sage journals. This subtype is more common in older olp patients 62. In llp, specifically, affected people develop itchy, purple, flattopped papules bumps in a linear distribution along the lines of blaschko. Lichen planus has been found to be associated with hepatitis c virus infection, chronic active hepatitis, and primary biliary cirrhosis. Lichen planus is not a dangerous disease, and it usually goes. These different forms can merge or coexist in the same patient. Feb 24, 2020 lichen planus lp is a selflimited disease that usually resolves within 812 months. Jul 01, 2011 lichen planus is a chronic, inflammatory, autoimmune disease that affects the skin, oral mucosa, genital mucosa, scalp, and nails.
Lichen planus lp is an inflammatory, pruritic disease of the skin and mucous membranes and can be generalized or localized. Oral lesions of lichen planus may also include bullae, but this is rare. May 17, 2014 lichen planus is a mucocutaneous disease characterized by nonspecific inflammation. Lichen planus is an inflammatory skin condition that can cause bumps or lesions to appear on your skin, in your mouth, or on your nails.
Lichen planus pigmentosus describes illdefined oval, greyish brown marks on the face and neck or trunk and limbs without an inflammatory phase. This disease has also later been reported from the middle east, latin america, korea, and japan, especially in people with darker skin. Erosive oral lichen planus involving the buccal mucosa. There is no known cause of lichen planus, and it usually. The papules may run together coalesce to form a larger raised surface plaque. Lichen planus lesions are described using the six ps. Diagnosis and treatment of lichen planus richard p. Lichen planus occurs when immune system mistakenly attacks skin cells or mucous membranes. Pdf factors affecting treatment outcomes in patients with oral. Oral lichen planus olp is the mucosal counterpart of cutaneous lp. While doctors dont know the cause of lichen planus, they do know that. On your skin, lichen planus causes a rash that is usually itchy. Lichen planus is a chronic inflammatory and immune mediated disease that affects the skin, nails, hair, and mucous membranes. Sep 10, 2015 rare lichen planus rare lp refers to several rare variants of lichen planus, which is a condition that affects the skin andor mouth.
Lichen planus lp is a chronic mucocutaneous disorder of the stratified squamous epithelium that affects oral and genital mucous membranes, skin, nails, and scalp. Lichen planus may also affect the scalp, the nails or the genitals. Lichen planus is a common disease that causes inflammation swelling and irritation on your skin or inside your mouth. Oral lichen planus olp is a chronic autoimmune disease sprinkled by t cells on the oral mucosal surface. Lichen planus health encyclopedia university of rochester. The signs and symptoms vary by subtype but generally include an itchy rash. It is derived from the greek word leichen0 means tree moss and latin word planus means flat. Diagnosis is usually clinical and supported by skin biopsy. Sedangkan pada daerah mukosa, seperti mulut atau vagina, penyakit ini ditandai dengan bercak putih yang kadang terasa nyeri. Cutaneous lichen planus on the flexor surface of the wrist. Lichen planus of the mouth, vagina, nails, and scalp rarely clears by itself and can cause permanent scarring. Diagnosis and treatment of lichen planus american family. My mother was told that the lichen planus could not be cured, but she had some uv type treatments, but the lichen planus was still as strong as ever.
Homeopathic treatment for oral lichen planus by dr. Lichen planus dermatologic disorders merck manuals. Lichen planus lp is a chronic inflammatory and immunemediated disease that affects the skin, nails, hair, and mucous membranes. A meta analysis study introduction oral lichen planus olp. Although lichen planopilaris is rare, it is one of the common causes of scarring hair loss of the. Lichen planus of the nails can cause brittle or split nails. The term lichen planus lp is derived from the greek word leichen meaning tree moss and the latin planus meaning. They later merge to form large hyperpigmented patches. Less commonly, lp may also involve the genitals penile or vulvar lp, scalp lichen. Although oral lichen planus predominantly occurs in adults older than 40 years, younger adults and children can also be affected.
The condition is characterized by erythematous areas and interspersed pseudomembranous areas. Cari tahu informasi medis lengkap dan terverifikasi tentang gejala, penyebab, cara mengobati, dan mencegah lichen planus di hello sehat. Metallothionein and stress combine to affect multiple or. It may sound like a fungal infection, but oral lichen planus is actually a chronic inflammatory skin condition in the mouth. Characteristic features include distinctive purplish, flattopped papules discrete or coalescent into plaques on the trunk and flexor surfaces. When lichen planus causes pain, burning, redness, blisters, sores, or ulcers, it can be treated. In addition, oral lichen planus may increase the risk.
Lichen planus affects primarily middleaged adults, and the prevalence is greater among women. The reason for this abnormal immune response is unknown. Pdf the pathogenesis of oral lichen planus researchgate. Lichen planus is a disease that can occur on the skin or inside the mouth. Oral lichen planus olp occurs more frequently than the cutaneous form and tends to be more persistent and more resistant to treatment. It is usually temporary, lasting 10 years, on average, and. The lesions are generally violaceous redpurple, slightly raised bumps papules with fine scales. Inside your mouth, it may cause burning or soreness.
Of 303 patients diagnosed with oral lichen planus, 58 19. Jul 15, 2015 linear lichen planus llp is a rare form of lichen planus, which is a condition that affects the skin andor mouth. There is currently no cure for oral lichen planus, and the painful symptoms may seriously impair quality of life. This disease of unknown etiology runs an insidious and prolonged course and is characterized by macules of dark brown colour distributed principally in the sunexposed areas of the body. It can be provoked by sun exposure, but it can also arise in sunprotected sites such as the armpits. It may be related to an allergic or immune reaction. Lichen planus british association of dermatologists. Current immunosuppressiv etherapies usually control oral mucosal. Most dental and medical practitioners see patients. Lichen planus is a chronic, inflammatory, autoimmune disease that affects the skin, oral mucosa, genital mucosa, scalp, and nails. Linear lichen planus genetic and rare diseases information.
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